TABLE 2.
Transcript-level cis-eQTLs on chromosome 15 for striatum and hippocampus
| Region | Gene | Chr | Location (Mb) | Location (cM) | P Value | FDR |
|---|---|---|---|---|---|---|
| Striatum | Zhx2 | chr15 | 4.31 | 1.95 | 3.1E-07 | 5.7E-03 |
| Zhx2 | chr15 | 4.99 | 1.983 | 3.1E-07 | 5.7E-03 | |
| Zhx2 | chr15 | 7.83 | 3.603 | 2.6E-07 | 4.8E-03 | |
| Zhx2 | chr15 | 8.12 | 3.702 | 2.6E-07 | 4.8E-03 | |
| Zhx2 | chr15 | 17.35 | 7.918 | 1.7E-07 | 3.4E-03 | |
| Zhx2 | chr15 | 21.04 | 8.263 | 6.5E-08 | 1.3E-03 | |
| Zhx2 | chr15 | 32.32 | 13.546 | 2.5E-13 | 7.3E-09 | |
| Zhx2 | chr15 | 57.11 | 23.8 | 6.6E-26 | 1.4E-20 | |
| Zhx2 | chr15 | 81.39 | 38.094 | 1.9E-09 | 4.7E-05 | |
| Zhx2 | chr15 | 84.44 | 39.864 | 3.9E-08 | 8.0E-04 | |
| Zhx2 | chr15 | 86.26 | 40.584 | 3.9E-08 | 8.0E-04 | |
| Hippocampus | Zhx2 | chr15 | 32.32 | 13.546 | 6.2E-09 | 2.7E-04 |
| Zhx2 | chr15 | 57.11 | 23.8 | 1.8E-13 | 7.2E-08 | |
| Zhx2 | chr15 | 81.39 | 38.094 | 5.4E-09 | 2.4E-04 | |
| Zhx2 | chr15 | 84.44 | 39.864 | 1.2E-07 | 4.5E-03 | |
| Zhx2 | chr15 | 86.26 | 40.584 | 1.2E-07 | 4.5E-03 |
Transcripts possessing significant eQTLs on chromosome 15 (FDR < 0.05) in the striatum and hippocampus. Bold rows indicate the peak location of each cis-eQTL, which in both cases is the same location as the QTL for brain [OMOR]. Analysis was conducted in 64 F2 mice (16 per sex per treatment), and analysis included sex, RNA extraction batch, and treatment as covariates.