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. 2022 Jul 26;16:2383–2393. doi: 10.2147/DDDT.S371596

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© 2022 Gao et al.

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Typical MRM chromatograms of nalbuphine (left panels) and IS (right panels). (A) blank plasma sample. (B) blank plasma sample spiked with nalbuphine at 0.1 ng/mL and IS at 10 ng/mL. (C) plasma sample from a patient after nalbuphine (15 mg) intravenous injection at 1.0 h.