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. 2022 Jul 26;4(1):vdac118. doi: 10.1093/noajnl/vdac118

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© The Author(s) 2022. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Overview of intraoperative, ex vivo, Raman spectra acquisition workflow. (A) Tissue resected using frameless stereotaxy. (B) Tissue sample placed in Solais device located in operating room. (C) Sample size limited to 2-4 mm per dimension (length × width × height) and placed on saline moistened telfa inside of petri dish. (D) Raman points selected for spectra acquisition. (E) Example of Raman spectra generated in seconds. (F) All tissue samples sent for individual histopathology review after Raman spectra acquisition.