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Tumor vs normal. (A) Representative tumor vs normal brain spectra with associated 95% confidence interval variance bands. (B) PCA-based two-dimensional sorting of tumor spectra from normal brain spectra. (C) ROC curve of a trained logistic regression model tasked with classifying tissue samples as either tumor or normal brain using LOPOCV. Abbreviations: LOPOCV, leave-one-patient-out cross-validation; PCA, principal component analysis, ROC, receiver-operating characteristic curve.
