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. 2022 Jul 18;13:939869. doi: 10.3389/fphar.2022.939869

TABLE 2.

Number and proportion of patients with and/or without concomitant prescriptions by drug class.

Prescription Categories Acetaminophen n = 24,395 Opioids n = 11,685 Sedatives n = 6,412 Anesthetics n = 5,541 Paralytics n = 679 Antidotes n = 473
Number of patients without concomitant prescription, n (%) 17,324 (71.0) 2002 (17.1) 200 (3.1) 1,626 (29.3) 9 (1.3) 91 (19.2)
Number of patients with and without concomitant prescription, n (%) * 5,868 (24.1) 4,363 (37.3) 454 (7.1) 860 (15.5) 9 (1.3) 40 (8.5)
Number of patients with concomitant prescription, n (%) 1,203 (4.9) 5,320 (45.5) 5,758 (89.8) 3,055 (55.1) 661 (97.3) 342 (72.3)
Number of patients with concomitant prescription by drug class, n (%)
 Opioids 6376 (26.1) - 5,888 (91.8) 3,174 (57.3) 623 (91.8) 301 (63.6)
 Sedatives 3,150 (12.9) 5,888 (50.4) - 1,480 (26.7) 541 (79.7) 252 (53.3)
 Anesthetics 2,183 (8.9) 3,174 (27.2) 1,480 (23.1) - 262 (38.6) 76 (16.1)
 Paralytics 284 (1.2) 623 (5.3) 541 (8.4) 262 (4.7) - 14 (3.0)
 Antidotes 263 (1.1) 301 (2.6) 252 (3.9) 76 (1.4) 14 (2.1) -
 acetaminophen - 6,376 (54.6) 3,150 (49.1) 2,183 (39.4) 284 (41.8) 263 (55.6)

Percentages were calculated with the total number of patients per drug class.*Patients could have multiple prescriptions for one drug class: some with and some without concomitant prescriptions of another drug class