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. 2022 May 25;32(4):578–585. doi: 10.1093/eurpub/ckac045

Table 2.

The influence of personal and work-related predictors on involuntary exit from paid employment in the development cohort (Lifelines, n = 55 950) and validation cohort (STREAM, n = 10 093)

Lifelines—development cohort
STREAM—validation cohort
Unemployment (n = 4628) C = 0.62 (0.61–0.63) Disability benefits (n = 954) C = 0.68 (0.66–0.70) Unemployment (n = 1435) C = 0.60 (0.58–0.62) Disability benefits (n = 449) C = 0.75 (0.73–0.77)
R 2 = 0.02 R 2 = 0.02 R 2 = 0.02 R 2 = 0.06
HR (95% CI) HR (95% CI) HR (95% CI) HR (95% CI)
Sociodemographic factors
 Age (per 10 years) 1.04 (1.01–1.08) 0.80 (0.75–0.86) 1.50 (1.34–1.68) 1.56 (1.27–1.93)
 Gender 1.21 (1.14–1.29) 1.74 (1.50–2.02) 1.07 (0.96–1.19) 1.28 (1.05–1.55)
 Marital status (in a relationship) 0.74 (0.68–0.80) 0.84 (0.71–1.01) 0.95 (0.97–1.25) 0.92 (0.75–1.15)
 Educational level (high = ref)
  Intermediate 1.03 (0.96–1.11) 1.24 (1.06 1.46) 1.10 (0.97–1.25) 1.41 (1.11–1.80)
  Low 1.29 (1.19–1.41) 1.73 (1.43–2.10) 1.14 (1.00–1.32) 1.58 (1.22–2.04)
Chronic disease
 CVD 2.64 (1.74–4.00) 1.59 (1.22–2.06)
 COPD 1.43 (1.07–1.90) 1.80 (1.39–2.34)
 Depression 1.43 (1.22–1.67) 2.51 (1.94–3.25) 1.51 (1.20–1.89) 3.20 (2.43–4.22)
 Diabetes 1.89 (1.34–2.68) 1.20 (0.86–1.66)
 Rheumatoid arthritis 3.05 (2.26–4.11) 2.54 (2.09–3.08)
Health behaviours
 Physical activity (0–7 days) 0.98 (0.96–0.99) 0.97 (0.95–1.00)
 Smoking 1.26 (1.17–1.35) 1.35 (1.16–1.57) 1.32 (1.17–1.49) 1.50 (1.22–1.84)
 Fruit intake (high = ref)
  Intermediate n/a n/a
  Low n/a n/a
 Vegetable intake (high = ref)
  Intermediate n/a n/a
  Low n/a n/a
 BMI (healthy weight = ref)
  Overweight 1.01 (0.95–1.08) 0.96 (0.83–1.11) 1.06 (0.94–1.20) 1.09 (0.87–1.37)
  Obese 1.21 (1.11–1.32) 1.39 (1.16–1.66) 1.14 (0.99–1.32) 1.35 (1.04–1.75)
Working conditions
 Quantitative demands
 Work pace
 Possibilities for development 1.06 (1.04–1.09) 1.07 (1.02–1.13) 1.02 (0.97–1.07) 1.03 (0.95–1.12)
 Meaning of work 1.12 (1.09–1.14) 1.03 (1.00–1.05)
 Influence at work 1.04 (1.00–1.09) 1.09 (1.02–1.16)
 Social support 1.11 (1.09–1.14) 1.07 (1.02–1.12) 1.11 (1.08–1.15) 1.04 (0.98–1.11)

Notes: n reflects number of workers who exit paid employment through this route; higher scores reflect poorer working conditions.

n/a indicates that this measure was not available in STREAM; STREAM included the following chronic diseases: heart disease, respiratory disease, psychological disease, diabetes and musculoskeletal disease; HR, hazard ratio.