Table 2.
Coding DNA sequences (CDS) identified in prophages potentially influencing host virulence or fitness.
| ERIC I | ERIC II | ERIC III | ERIC IV | ERIC V | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| CDS | Host 3 | Host 5 | Host 6 | Host 10 | Host 9 | Host 13 | Host 11 | Host 7 | Host 8 | Host 12 | Host 14 |
| TetR family transcriptional regulator (TetR/AcrR) | |||||||||||
| β-Lactamase superfamily domain [metal β-lactamases (MBL) fold metallo-hydrolase Yycl] | |||||||||||
| β-Lactamase inhibitory proteins (BLIP) | |||||||||||
| ATP-binding cassette (ABC) group | |||||||||||
| Aromatic acid exporter family protein | * | ||||||||||
| Major facilitator superfamily (MFS) transporter | |||||||||||
| Multidrug efflux small multidrug resistance (SMR) transporter | |||||||||||
| Efflux transporter-like protein | * | ||||||||||
| Iron–sulfur (Fe-S) cluster assembly protein SufB | * | * | |||||||||
| NifU family iron–sulfur (Fe-S) cluster assembly protein—SUF system | * | * | |||||||||
| Metal β-lactamases (MBL) fold metallo-hydrolase | |||||||||||
| Phosphomannomutase | |||||||||||
| Transglycosylase | |||||||||||
| Toxin HicA | |||||||||||
| Antitoxin HicB | |||||||||||
| Antitoxin MazE | |||||||||||
| Antitoxin SocA | * | ||||||||||
| AbrB/MazE/SpoVT family DNA-binding domain-containing protein | |||||||||||
| Bacterial toxin 44 | * | ||||||||||
| Toxin | |||||||||||
| Toxin-like protein | * | ||||||||||
| Bacteriocin biosynthesis protein | * | ||||||||||
| Epsilon-toxin type B (EtxB) | |||||||||||
| Leukocidin LukF-PV precursor = leukotoxin | |||||||||||
| Closticin | * | ||||||||||
| DNA internalization-related competence protein ComEC/Rec2 | * | * | |||||||||
| Segregation and condensation protein B (ScpB) | |||||||||||
| YopX family protein | |||||||||||
| Enhancin / phosphohydrolase | * | ||||||||||
| Virulence-associated protein E | |||||||||||
| ImmA/IrrE family metallo-endopeptidase | |||||||||||
| Esterase family protein | * | ||||||||||
| S8 family serine peptidase | |||||||||||
| Histidine kinase-like protein | * | ||||||||||
| Pyruvate dehydrogenase E1 component subunit alpha | * | ||||||||||
| Metallopeptidase | |||||||||||
| FtsX-like permease family protein | * | ||||||||||
| GlcNAc-chitin binding protein (GbpA) | * | ||||||||||
| Dipeptidyl aminopeptidase/acylaminoacyl-peptidase | |||||||||||
| GTP pyrophosphokinase-like protein | * | ||||||||||
| Host-nuclease inhibitor protein Gam (Gam) | |||||||||||
| MazG-like nucleotide pyrophosphohydrolase | * | ||||||||||
| VRR-NUC domain-containing protein | |||||||||||
| YifB family Mg chelatase-like AAA ATPase | * | * | * | ||||||||
| YncE family protein | * | ||||||||||
| YxeA family protein | |||||||||||
| Coat protein | |||||||||||
| Iron-containing alcohol dehydrogenase | * | ||||||||||
| Ketopantoate hydroxymethyltransferase | |||||||||||
| Membrane protein | * | ||||||||||
| Outer spore coat protein (CotE) | * | ||||||||||
| Spore protease YyaC | * | * | * | * | |||||||
| Sporulation protein YhbH | * | ||||||||||
| Stress protein | * | * | * | * | |||||||
| DNA mismatch repair protein MutS | * | ||||||||||
| ERF superfamily protein | |||||||||||
| Acetyltransferase | |||||||||||
| dCMP deaminase family protein | * | * | |||||||||
| Murein transglycosylase-like protein | * | ||||||||||
| NTP-binding protein | * | ||||||||||
| Peptidase domain | * | ||||||||||
| Phenylalanine racemase | |||||||||||
| Phosphatidylglycerophosphatase A (PgpA) | * | ||||||||||
| Phosphatidylserine decarboxylase | * | ||||||||||
| STAS-like domain-containing protein | * | ||||||||||
| Thiamin pyrophosphokinase | * | ||||||||||
| Thioredoxin reductase | * | ||||||||||
| YqaE/Pmp3 family membrane protein | |||||||||||
The gray color identifies the corresponding CDS in the respective ERIC genotype. *CDS only found in this genotype.