FIG. 1.

Alignment of the active site regions of PTS IIA and non-PTS IIA protein domains. ∗, conserved residue; :, similar residue; s, salt bridge with residue in glycerol kinase; h, hydrophobic interaction with glycerol kinase; z, coordination of Zn(II) (7); @, charged group near phosphorylation site. Only a portion of each PTS IIA protein domain in the SwissProt database is shown. Two-letter suffixes denote S. thermophilus (St), Pseudomonas aeruginosa (Pa), Lactobacillus bulgaricus (Lb), Leuconastoc lactis, (Ll), S. typhimurium (Sty), E. coli (Ec), B. subtilis (Bs), Klebsiella pneumoniae (Kp), Brevibacterium lactofermentum (Bl), and Corynebacterium glutamicum (Cg).