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. 2022 Jun 26;13(6):14159–14174. doi: 10.1080/21655979.2022.2083855

Figure 2.

Figure 2.

Malignancy of OS cells was affected by miR-331-3p. (a) RT-qPCR was utilized to quantify miR-331-3p expression in miR-331-3p mimic and miR-331-3p inhibitor group. (b) Following treatment with the miR-331-3p mimic or inhibitor, U2OS and saos-2 cells proliferation ability were assessed. (c and d) Migration and invasion abilities were quantified in U2OS and saos-2 cells transfected with the miR-331-3p mimic or miR-331-3p inhibitor, respectively. (e) Cell migration was observed at 0, 24, 48, 72 hours after scratching the cell layers. *P < 0.05, **P < 0.01 and ***P < 0.001.