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. 2022 Jun 26;13(6):14562–14577. doi: 10.1080/21655979.2022.2090608

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — KEGG pathway analysis of DEGs, PPI network construction and hub gene identification (a) KEGG pathway enrichment scatter diagram in WT and WT + sevoflurane group. (b) KEGG pathway enrichment scatter diagram in IL-17A^−/− and IL-17A^−/− + Sev group. (c) The protein–protein interaction network of DEGs in WT and WT + sevoflurane group. (d)Ten hub genes with the highest degree in WT and WT + sevoflurane group(Red square indicates a higher degree, and yellow square indicates a lower degree). (e) GSEA gene enrichment analysis diagram. (f) Differential expression of IL-17 was confirmed by RT-PCR. Data are expressed as mean ± SD. Compared with WT group, *P < 0.05.