Table 3.

The MAF and HWE of Candidate SNPs Between Lung Cancer Cases and Healthy Controls

SNP	Gene	MAF-Case	MAF-Control	HWE p	OR (95% CI)	p
rs2233914	SLC31A1	0.35	0.33	0.86	1.075(0.914–1.264)	0.385
rs10981694	SLC31A1	0.24	0.17	0.22	1.455(1.201–1.763)	0.00012*
rs10488764	FDX1	0.30	0.23	0.57	1.483(1.244–1.768)	0.00001*
rs1061472	ATP7B	0.41	0.40	0.46	1.066(0.911–1.247)	0.424
rs9535826	ATP7B	0.32	0.40	0.19	0.714(0.608–0.838)	0.00004*
rs9535828	ATP7B	0.34	0.43	0.75	0.679(0.579–0.796)	0.00001*

Note: *Bonferroni multiple adjustment was applied, with p ≤ 0.008.

Abbreviations: SNP, single-nucleotide polymorphism; MAF, minor allele frequency; HWE, Hardy–Weinberg equilibrium.