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. 2022 Aug 1;99(6):959–983. doi: 10.1007/s11524-022-00665-z

Table 2.

Studies assessing the association between historical HOLC grade and subsequent environmental determinants of health

Location Outcome(s) Unit of analysis (sample size) HOLC variable Control variables Abbreviated findings
Hoffman et al. [48] 108 urban areas nationwide

(1) Summertime land surface temperature (LST)

(2) Developed impervious surface land cover

(3) Tree canopy coverage

HOLC polygons (N not stated) Categorical: A, B, C, D None LST was elevated in D- relative to A-graded areas in 94% of urban areas (2.6 °C warmer on average). Impervious surface land cover was higher in D-graded areas and tree canopy cover was lower
Lane et al. [43] 202 urban areas nationwide Annual ambient concentration predictions of (1) nitrogen dioxide (NO2) and (2) fine particulate matter (PM2.5) Census block (N = 562,078) Categorical: A, B, C, D None Across all cities, NO2 concentrations are 56% higher in D-graded areas than A-graded areas, while PM2.5 concentrations are 4% higher. Population-weighted mean NO2 levels were higher in D-graded areas than overall in 80% of cities (55% for PM2.5), and were lower in A-graded areas than overall in 84% of cities (68% for PM2.5)
Lee et al. [25] 6 cities, San Francisco Bay Area, CA Density of off-premise alcohol outlets Census block groups (N = 520) Categorical: A (ref), B, C, D, ungraded Local and adjacent population, median household income D grade was associated with higher density of off-premise alcohol outlet density relative to A grade (RR = 1.90 [0.81, 4.84])
Li & Yuan [31] 102 urban areas nationwide mRFEI Index of healthiness of the food environment, ranging from 0 (worst) to 100 (best) Census tract (N = 11,651) Categorical: A (ref), B, C, D, ungraded (< 50% of land graded) CT sociodemographic characteristics and population density, city-level racial segregation and natural log of the population D-graded areas had 0.83 [0.77, 0.97] times the mRFEI score of A-graded areas
Locke et al. [63] 37 urban areas, with sub-analysis of 8 Tree canopy coverage HOLC polygon (N = 3188) Categorical: A (ref), B, C, D City random effect D grade was associated with decreased percent tree canopy cover relative to A grade (M =  − 20.79 percentage points [− 22.27, − 19.31])
Nardone et al. [45] 102 urban areas nationwide Summer and annual average NDVI, ranging from -1 (least green) to 1 (most green) HOLC polygon (N = 4141) Categorical: adjacent grades (B vs. A, C vs. B, and D vs. C) 1940 CT sociodemographic characteristics, 1940 population density, ecoregion, Census region Unadjusted annual average mean NDVI increased on a gradient from D to A grade. Poorer HOLC grade was associated with a 0.024–0.39 unit decrease in annual average NDVI compared to the adjacent grade in adjusted models using a restricted, propensity score matched sample
Nowak et al. [77] All available cities nationwide Tree cover, impervious cover, tree cover stocking (proportion of non-impervious area occupied by tree canopies), and ecosystem service value (pollution removal, carbon sequestration, avoided runoff) Census incorporated and designated places (N = 1259) Categorical: A, B, C, D None Poorer grade was associated with lower % tree cover, % stocking, and ecosystem service values, and higher % impervious cover. For example, tree cover was about twice as high a proportion of A-graded areas as D-graded areas. 88.6% of cities had greater % tree cover, and 86.4% had lower % impervious cover, in A-graded areas than D-graded areas
Sadler et al. [47] Baltimore, MD Healthy food access score ranging from 1 to 1145 Residential tax parcels (N not stated) Continuous variable with change from A to B, B to C, and C to D considered 1 unit increase Socioeconomic distress index, racial composition, housing age A 1-unit increase in redlining was associated with a 48–52 point increase in food access score
Saverino et al. [41] Richmond, VA Afternoon mean temperature during a heat wave Census block group (N not stated) Continuous: quartiles of proportion A/B combined and C/D combined None Areas in the fourth quartile of percentage C- or D-graded were on average 0.53 °C warmer than areas in the lowest quartile, while areas in the fourth quartile of percentage A- or B-graded were on average 0.26 °C cooler than areas in the lowest quartile
Schinasi et al. [46] Philadelphia, PA Land cover and housing characteristics linked to enhanced heat vulnerability, including roof color, shape, and shape and color combined, and presence of immediately adjacent mature or immature tree canopy Residential properties (N = 400) Categorical: A (ref), B, C, D 1940 racialized economic segregation and CT sociodemographic characteristics Compared to properties in A-graded areas, properties in D-graded areas had elevated risk of low or no mature tree canopy, in both models adjusting for historic characteristics (RR = 5.09 [2.78–9.32]) and for present-day characteristics (RR = 5.96 [5.76, 6.16])
Schwartz et al. [35] 13 Ohio urban areas Tobacco retailer density Modified CTs (N = 3846) Categorical: A (ref), B, C, D, ungraded; all pairwise comparison CT sociodemographic characteristics, city fixed effect D grade was associated with higher density of tobacco retailers relative to A (RR = 1.98 [1.52, 2.60])
Trangenstein et al. [78] Baltimore, MD Clusters of four types of alcohol outlets Census block groups (N = 537) Categorical: B, C, D, ungraded (ref) Population density, sociodemographic characteristics, concentrated disadvantage index, residential stability, social control or disinvestment, built environment characteristics Compared to ungraded areas, D grade was associated with higher odds of being in a general (OR = 8.82 [2.99, 25.98]), off-premise (OR = 7.32 [2.00, 26.79]), on-premise (OR = 8.07 [2.26, 28.77]), or LBD-7 (combined on/off-premise) (OR = 8.60 [2.93, 25.30]) alcohol outlet cluster
Wilson [79] Baltimore, MD; Dallas, TX; Kansas City, MO 1) LST, two summer days and 2) NDVI, two summer days HOLC polygons Categorical: A, B, C, D None C- and D-graded areas had higher median land surface temperatures than A or B in all cities (P < 0.01, Kruskal–Wallis test). Mean NDVI was lower in C- and D-graded areas compared to A- and B-graded areas in all cities

NDVI normalized difference vegetation index; OR risk ratio; RR risk ratio