Table 3.
Patient Characteristics and Analyses for the Secondary Outcome of Endotracheal Intubation
| Variables | Intubation | Unadjusted | Adjusteda | |
|---|---|---|---|---|
| Yes, n=151 | No, n=3185 | OR (95% CI) | OR (95% CI) | |
| Continuous | Median (IQR) | Median (IQR) | ||
| Age, year | 3.2 (1.1–8.8) | 6.0 (2.6–12.5) | 0.94 (0.91–0.97) | 0.97 (0.92–1.02) |
| Hemoglobin, g/dL | 11.9 (10.4–13.1) | 11.5 (10.0–13.0) | 1.05 (0.98–1.13) | – |
| Arrival to IVF, minutes | 26 (17–45) | 46 (29–75) | 0.82 (0.75–0.91) | 0.92 (0.82–1.03) |
| Arrival to antibiotic, minutes | 53 (37–86) | 74 (49–129) | 0.88 (0.83–0.94) | 0.97 (0.89–1.05) |
| Total bolus volume, mL | 408 (200–834) | 524 (300–1000) | 0.99 (0.99–1.00) | 0.99 (0.98–1.0) |
| Bolus rate, mL/kg/hr | 48.7 (24.3–90) | 26.1 (16.4–46.2) | 1.19 (1.14–1.25)* | 1.25 (1.09–1.44)* |
| Categorical | N (column %) | N (column %) | ||
| Sex, male | 94 (62.3) | 1558 (48.9) | 1.72 (1.23–2.40)* | 1.80 (1.23–2.63)* |
| ICU admission | 145 (96.0) | 1110 (34.9) | 45.18 (19.90–102.55)* | 74.92 (23.63–237.49)* |
| Hypotension | 13 (8.6) | 162 (5.1) | 1.85 (1.02–3.34)* | 1.00 (0.53–1.92) |
| Vasoactive agent started | 37 (24.5) | 252 (7.9) | 3.80 (2.57–5.64)* | 1.86 (1.17–2.95)* |
Notes: aAdjusted model includes age, sex, total bolus volume, ICU admission, hypotension, vasoactive agent, and quadratic term for bolus rate (all were p<0.05); Adjusted model used n=3159 observations due to missing values for confounding variables *p<0.05.
Abbreviations: CI, confidence interval; g/dL, grams per deciliter; IQR, interquartile range; mL, milliliters; mL/kg/hr, milliliters per kilogram per hour; NIPPV, non-invasive positive pressure ventilation; OR, odds ratio.