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. 2022 Jul 28;15:4303–4314. doi: 10.2147/JIR.S371045

Table 3.

Relationship Between PNI and Classification of NYHA

Variables NYHA Class II
β ORa (95% CI) β ORb (95% CI) β ORc (95% CI)
PNI −0.004 0.996(0.990–1.002) 0.001 1.001(0.995–1.007) 0.005 1.005(0.999–1.012)
Normal (PNI≥38) Reference Reference Reference
Moderate (35<PNI<38) 0.018 1.019(0.755–1.375) 0.035 1.035(0.764–1.402) −0.030 0.971(0.713–1.323)
Severe (PNI≤35) 0.014 1.014(0.727–1.414) 0.077 1.081(0.771–1.513) 0.073 1.076(0.762–1.519)
NYHA class III
β ORa (95% CI) β ORb (95% CI) β ORc (95% CI)
PNI −0.084 0.920(0.912–0.927)** −0.076 0.927(0.919–0.935)** −0.067 0.935(0.927–0.944)**
Normal (PNI≥38) Reference Reference Reference
Moderate (35<PNI<38) 1.314 3.720(2.744–5.042)** 1.257 3.514(2.576–4.794)** 1.098 2.997(2.165–4.148)**
Severe (PNI≤35) 1.698 5.466(3.970–7.525)** 2.005 5.577(4.024–7.730)** 1.586 4.883(3.455–6.901)**
NYHA class IV
β ORa (95% CI) β ORb (95% CI) β ORc (95% CI)
PNI −0.147 0.863(0.850–0.877)** −0.138 0.871(0.857–0.886)** −0.124 0.883(0.868–0.899)**
Normal (PNI≥38) Reference Reference Reference
Moderate (35<PNI<38) 2.075 7.968(5.283–12.018)** 1.955 7.067(4.639–10.767)** 1.691 5.422(3.469–8.578)**
Severe (PNI≤35) 2.153 8.613(5.526–13.424)** 2.145 8.545(5.431–13.444)** 1.882 6.564(4.043–10.658)**

Notes: Model a: unadjusted; Model b: adjusted for age, sex, SBP, DBP, FBG; HbA1c, Model c: adjusted for age, sex, SBP, DBP, FBG; HbA1c, TC, TG, HDL-C, LDL-C, smoking, drinking, hypertension, hyperlipidemia, use of antihypertensives, and use of antilipidemic, Compared with NYHA class I, **P<0.01.

Abbreviations: OR, odds ratio; CI, confidence interval; β, regression coefficient; IQR, interquartile range; NYHA, New York Heart Association; PNI, prognostic nutrition index.