Table 1.
Patient Background Data (n=11)
Backgrounds | Median [Interquartile Range] or Number (%) |
---|---|
Age, years | 64.6 [60.0–75.1] |
Sex, Male/Female | 2 (18.2)/9 (81.8) |
Time from diagnosis until the initiation of treatment, years | 13.7 [6.3–15.8] |
Weight, kg | 49.4 [44.7–51.5] |
BMI, kg/m2 | 19.8 [16.4–22.4] |
Smoking history | 2 (18.2) |
Medical history | |
Bronchial asthma | 2 (18.2) |
Malignancy | 2 (18.2) |
Diabetes mellitus | 1 (9.1) |
Mycobacterium species | |
M. avium | 10 (90.9) |
M. intracellulare | 1 (9.1) |
Presence of cavitary lung lesions | 4 (36.4) |
Radiological pattern | |
NB/FC/NB+FC/unclassified | 8 (72.7)/0 (0)/3 (27.3)/0 (0) |
Number of GBT drugs in regimen (at baseline) | |
0/1/2/3/4 or more | 0 (0)/0 (0)/5 (45.5)/4 (36.4)/2 (18.2) |
Drug class (at baseline) | |
Macrolide | 9 (81.8) |
Ethambutol | 10 (90.9) |
Rifamycin | 8 (72.7) |
Fluoroquinolone | 3 (27.3) |
Others | 0 (0) |
Generic name of drug (at baseline) | |
Clarithromycin | 3 (27.3) |
Azithromycin | 3 (27.3) |
Erythromycin | 3 (27.3) |
Ethambutol | 10 (90.9) |
Rifampicin | 8 (72.7) |
Sitafloxacin | 3 (27.3) |
Abbreviations: FC, fibrocavitary type; GBT, guideline-based therapy; NB, nodular bronchiectatic type.