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Schematic illustration of 68Ga-Nb1159 binding to the RBD and PET imaging. (a) 68Ga-Nb1159 and the neutralizing nanobody Nb11-59 may bind to the SARS-CoV-2 RBD to block the interaction of the SARS-CoV-2 RBD and ACE2 receptor. (b) Schematic illustration of the mice model of treatment with the SARS-CoV-2 RBD and timeline for PET/CT imaging after 68Ga-Nb1159 i.v. injection.
