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. 2022 Jun 8;36(8):2050–2063. doi: 10.1038/s41375-022-01617-x

Fig. 7. MiR-146a targets CD147 in ALK+ ALCL promoting increased energy metabolism.

Fig. 7

NPM-ALK promotes CD147 expression by downregulation of miR-146a and overexpression of C/EBPβ through the STAT3 signaling pathway [33]. CD147 promotes tumor growth and invasion by enhancing aerobic glycolysis in ALK+ ALCL.