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. 2022 Jul 30;52:101579. doi: 10.1016/j.eclinm.2022.101579

Figure 4.

Figure 4

Antibodies to PfCSP by ELISA (serum dilution at which the optical density was 1.0).

A: Geometric Mean Time Trends of Anti-PfCSP ELISA OD 1.0 with 95% Confidence Intervals by Treatment Group PP Population. Red line represents the Anti-PfCSP ELISA OD 1.0 for vaccine group and the blue line represents the Anti-PfCSP ELISA OD 1.0 for control group. Population analysed: 29 in vaccine group and 30 in control group.

B: Additive Change (net OD 1.0) from Baseline of Anti-PfCSP ELISA OD 1.0 by Treatment Group, PP Population. The filled red circles represent the uninfected and the unfilled red circles represent the infected. The blue lines represent the median ratio OD 1.0 and interquartile ranges.

C: Multiplicative Change from Baseline of Anti-PfCSP ELISA OD 1.0 by Treatment Group PP Population. The solid red circles represent the multiplicative change from baseline at 12 Days Post Dose 1 of the Anti-PfCSP antibodies and the light circle represent the control group. The blue lines represent the median ratio OD 1.0 and interquartile ranges.