Fig. 6. Evaluation of Gi-protein-coupled receptor hM4Di expression (with mCherry reporter) in human nuclear antigen-positive (HNA+) cells, neuron-specific nuclear antigen-positive (NeuN+) neurons, and gamma-aminobutyric acid-positive (GABA+) interneurons derived from human medial ganglionic eminence progenitor cell grafts in the hippocampus of chronically epileptic rats.

Note that mCherry is displayed in virtually all HNA+ graft-derived cells (a–c), NeuN+ neurons (d–f), and GABA-ergic interneurons (j–l). g–i demonstrate that a vast majority (mean ± S.E.M, 80.8 ± 1.1%) of HNA+ graft-derived cells differentiated into GABA-ergic interneurons. Scale bars: a–l, 20 µm.