Table 1.

Patient demographics and select baseline characteristics

Patient variable		Case	Control	Odds ratio (OR)*	95% CI	Fisher P-value
		(N = 85)	(N = 160)
Sex	Female	40 (47.1%)	76 (47.5%)
	Male	45 (52.9%)	81 (50.6%)
	Missing	0 (0.0%)	3 (1.88%)
Median age (range)		60 (83–25)	59 (85–27)
Infection site	Blood	39 (45.9%)
	Respiratory	19 (22.4%)
	Urine	23 (27.1%)
	Other	4 (4.71%)
Mean weighted Elixhauser score (±SD)		22.2 ± 11.6	19.7 ± 11.9	1.02	0.994 to 1.04	0.127
Depression	Yes	30 (35.3%)	44 (27.5%)	1.31	0.761 to 2.26	0.327
	No	55 (64.7%)	113 (70.6%)
	Missing	0 (0.0%)	3 (1.88%)
Prior diuretics	Yes	30 (35.3%)	38 (23.8%)	1.69	0.905 to 3.05	0.101
	No	55 (64.7%)	119 (74.4%)
	Missing	0 (0.0%)	3 (1.88%)
Prior Vitamin D	Yes	18 (21.2%)	19 (11.8%)	1.66	0.972 to 4.44	0.0591
	No	67 (78.8%)	138 (86.3%)
	Missing	0 (0.0%)	3 (1.88%)
Prior pressors/inotrope	Yes	20 (23.5%)	14 (8.75%)	3.06	1.40 to 6.68	0.00502
	No	65 (76.6%)	143 (89.4%)
	Missing	0 (0.0%)	3 (1.88%)
High-risk antibiotics	Yes	30 (35.3%)	32 (20.0%)	2.21	1.18 to 4.14	0.013
	No	55 (64.7%)	125 (78.1%)
	Missing	0 (0.0%)	3 (1.88%)
Albumin	<2.5 g/dL	35 (41.2%)	34 (21.3%)	2.86	1.49 to 5.48	0.00157
	≥2.5 g/dL	47 (55.3%)	116 (72.5%)
	Missing	3 (3.53%)	10 (6.25%)

*Two-sided test. No adjustments were made for multiple comparisons. OR for sex was incalculable due to use of sex as a matching variable.

Bold text indicates significant results (P-value ≤ 0.01 after adjustment for clinical variables).