Table 2.
Vaccine effectiveness | Group | Cost (US$) | Effectiveness (No. of events) |
Incremental cost (US$) |
Incremental effectiveness (No. of events) |
ICER (US$/event) |
---|---|---|---|---|---|---|
Against infection (RCT) | Two doses | 168,553,644,312 | 39,166,629 | −352,229,625,481 | 93,872,193 | −3,752 |
Non-vaccination | 520,783,269,793 | 133,038,822 | / | / | / | |
Against infection (RWE) | Two doses | 196,571,784,227 | 46,324,118 | −324,211,485,566 | 86,714,704 | −3,739 |
Non-vaccination | 520,783,269,793 | 133,038,822 | / | / | / | |
Against hospitalization (RCT) | Two doses | 15,235,049,685 | 0 | −308,329,723,032 | 24,612,182 | −12,528 |
Non-vaccination | 323,564,772,717 | 24,612,182 | / | / | / | |
Against hospitalization (RWE) | Two doses | 82,860,087,183 | 5,143,946 | −240,704,685,534 | 19,468,236 | −12,364 |
Non-vaccination | 323,564,772,717 | 24,612,182 | / | / | / | |
Against ICU admission (RWE) | Two doses | 29,877,607,019 | 596,519 | −123,608,318,918 | 5,656,305 | −21,853 |
Non-vaccination | 153,485,925,937 | 6,252,825 | / | / | / | |
Against death (RWE) | Two doses | 22,083,877,846 | 278,430 | −29,372,381,818 | 1,813,456 | −16,197 |
Non-vaccination | 51,456,259,664 | 2,091,886 | / | / | / |