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. 2022 Jul 19;10:917732. doi: 10.3389/fpubh.2022.917732

Table 2.

Cost-effectiveness of inactivated vaccine against COVID-19 infection, hospitalization, ICU admission, and death.

Vaccine effectiveness Group Cost (US$) Effectiveness (No. of events) Incremental cost
(US$)
Incremental effectiveness (No. of events) ICER
(US$/event)
Against infection (RCT) Two doses 168,553,644,312 39,166,629 −352,229,625,481 93,872,193 −3,752
Non-vaccination 520,783,269,793 133,038,822 / / /
Against infection (RWE) Two doses 196,571,784,227 46,324,118 −324,211,485,566 86,714,704 −3,739
Non-vaccination 520,783,269,793 133,038,822 / / /
Against hospitalization (RCT) Two doses 15,235,049,685 0 −308,329,723,032 24,612,182 −12,528
Non-vaccination 323,564,772,717 24,612,182 / / /
Against hospitalization (RWE) Two doses 82,860,087,183 5,143,946 −240,704,685,534 19,468,236 −12,364
Non-vaccination 323,564,772,717 24,612,182 / / /
Against ICU admission (RWE) Two doses 29,877,607,019 596,519 −123,608,318,918 5,656,305 −21,853
Non-vaccination 153,485,925,937 6,252,825 / / /
Against death (RWE) Two doses 22,083,877,846 278,430 −29,372,381,818 1,813,456 −16,197
Non-vaccination 51,456,259,664 2,091,886 / / /