Table 1.
Comparisons of Psychoneurological Symptoms Pre-(T1) and Post-(T2) Chemotherapy Cycle.
| Variable | T1 (n = 40) | T2 (n = 39) d | p-value |
|---|---|---|---|
| Pain (mean [SD]) | 41.8 (9.2) | 41.5 (9.0) | .80 a |
| Fatigue (mean [SD]) | 44.9 (13.8) | 43.7 (14.3) | .53 a |
| Anxiety (mean [SD]) | 43.9 (11.0) | 42.4 (11.8) | .26 a |
| Depressive symptoms (mean [SD]) | 46.0 (12.0) | 43.9 (10.5) | .11 a |
| Pain group (T score ≥50 vs.<50), n (%) | 6 (15) versus 34 (85) | 8 (20.5) versus 31 (79.5) | .63 b |
| Fatigue group (T score ≥50 vs.<50), n (%) | 14 (35) versus 26 (65) | 15 (38.5) versus 24 (61.5) | .99 b |
| Anxiety group (T score ≥50 vs. <50), n (%) | 11 (27.5) versus 29 (72.5) | 8 (20.5) versus 31 (79.5) | .45 b |
| Depressive symptoms group (T score ≥50 vs. <50), n (%) | 13 (32.5) versus 27 (67.5) | 12 (30.8) versus 27 (69.2) | .99 b |
| PNS cluster across groups, n (%) | <0.0001 c | ||
| 0 | 23 (29.1) | 18 (46.2) | |
| 1 | 2 (2.5) | 9 (23.1) | |
| 2 | 8 (10.1) | 5 (12.8) | |
| 3 | 4 (5.1) | 4 (10.3) | |
| 4 | 3 (3.8) | 3 (7.7) |
Note. T1, pre-chemotherapy; T2, post-chemotherapy. PNS, psychoneurological symptoms; SD, standard deviation.
aPaired t-test.
bMcNemar test.
cChi-Square test.
d One patient with missing data of PNS post-chemotherapy, thus, our analyses were conducted for 39 patients.