Fig. 3.

Anxiety-like behaviour was not altered between treatment groups. During the Elevated Pus Maze Test (A) numerous parameters like the time spent in different body elongation states (B), the total time the mouse was moving or not moving (C) and the total time spent either in open or closed arms (D) were measured and analysed. None of the investigated parameters changed significantly between platelet depletion and control animals at any analysed time point. Heatmaps generated from data collected at day 21 post ischaemia are used to visualise the areas mice reside the most, with red coloured areas meaning more time spent and blue coloured areas less time spent (E). In case of normal distribution unpaired, two-tailed Student's t-test corrected by Holm-Sidak method was used for statistical analysis, otherwise Mann-Whitney-U test was applied. N = 17/17. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)