Fig. 6.

Light sheet analysis of whole brains did not expose any changes in the cerebral vascular system. Mice were sacrificed at 28 dpi and whole brains prepared for light sheet analysis of the vascular system. Vessel length, number of branching points, mean branch length and tortuosity were evaluated. None of the parameters were altered in any of the treatment groups (A). Representative images were taken to visualise differences between the ipsi- and contralesional hemispheres (B). In case of normal distribution unpaired, two-tailed Student's t-test corrected by Holm-Sidak method was used for statistical analysis, otherwise Mann-Whitney-U test was applied. Scale bar indicates 50 μm. N = 5/6.