Fig. 7.

Flow cytometry analysis of whole brains revealed no differences in the abundance of various immune cell subsets 28 dpi. Whole brains from 28 dpi were used to investigate infiltrated immune cells in both groups (A). Both treatment groups did not show differences the number of infiltrated lymphocytes (B), neutrophils (C). Besides, proportion of T cells (D), including T-cell subclasses (E, F) were not altered in the brain parenchyma of platelet depleted or isotype treated animals. In case of normal distribution unpaired, two-tailed Student's t-test corrected by Holm-Sidak method was used for statistical analysis, otherwise Mann-Whitney-U test was applied. N = 8/8.