Figure 3. Neurological Disease Burden Analysis for p.C282Y Homozygotes.

A, Sex-agnostic and sex-stratified effect of C282Y homozygosity for neurological disorders. Labels in parentheses indicate International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), codes or ranges of ICD-10 codes for categories of diagnoses. The dotted vertical line indicates an odds ratio (OR) of 1, ie, null effect. B, Plots indicating diagnosis overlap for C282Y homozygote male individuals of hemochromatosis and movement disorders or other disorders of the nervous system.³⁸