Table 2.

Biomarkers of brain injury by day and their correlation with new functional impairment

		N	Median (IQR)	Correlation coefficient (ρ)	p-value
Neuron Specific Enolase
	Day 0	42	354.50 (147.50-568.75)	.32	.044
	Day 1	42	204.00 (100.00-585.50)	.10	.552
	Day 3	37	253.50 (102.00-560.25)	−0.02	.900
	Day 5	27	202.50 (84.50-568.50)	−0.13	.539
	Hospital discharge	28	268.75 (161.50-837.75)	−0.31	.111
S100b
	Day 0	42	10.25 (4.75-27.13)	.19	.236
	Day 1	42	8.00 (3.00-15.50)	.02	.928
	Day 3	37	8.00 (4.00-14.50)	−.04	.801
	Day 5	27	7.00 (5.00-18.00)	.14	.510
	Hospital discharge	28	7.50 (3.00-18.50)	−.15	.462