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. 2022 Jul 19;9:849723. doi: 10.3389/fmolb.2022.849723

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Copyright © 2022 Deng, Chen, Ren, Zeng, Zhang, Li, Tang and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The associations of the B7-CD28 family-based signature with inflammatory activities (A,B), Treg signatures expression (C,D) and several checkpoint members (E). ∗∗∗∗ represents p < 0.0001 in TCGA and mRNAseq_325 cohorts.