Table 2.

Univariate and multivariate analyses to identified factors predicting severe PHLF

Variables	Odds ratio	95% CI	P value	Odds ratio	95% CI	P value
PALBI	6.98	2.07–23.6	0.0021*	3.81	0.65–22.3	0.1385
FIB-4 index	1.03	0.99–1.06	0.1674
APRI	1.36	1.15–1.62	0.0009**	1.32	1.05–1.65	0.0230*
ALPlat index	0.99	0.98–0.99	0.0106*	0.99	0.99–1.00	0.9852
ICG-R15 (%)	1.05	1.01–1.08	0.0070*	1.02	0.97–1.06	0.4890
MELD score	1.43	1.221.68	< 0.0001**	1.44	1.15–1.80	0.0020*
Operating time (min)	1.01	1.00–1.01	< 0.0001**	1.01	1.00–1.01	0.0019*
Intraoperative blood loss (mL)	1.00	1.00–1.00	< 0.0001**	1.00	1.00–1.00	0.0278*

ALPlat index platelet count + 90 × albumin, APRI AST-to-platelet ratio index, AST asparate aminotransferase, CI confidence interval, FIB-4 fibrosis-4, ICG-R15 indocyanine green dye retention rate at 15 min, MELD model for end-stage liver disease, PALBI platelet-albumin-bilirubin, PHLF posthepatectomy liver failure *P < 0.05 and **P < 0.001