Fig. 1.

Relationship between dyslipidemia and GVHD (designed with BioRender). A: Preconditioning results in tissue damage, releasing of various inflammatory factors, expansion, and differentiation of T cells. B: GVHD leads to a decrease in serum HTGL content, makes triglyceride fail to break down, and ultimately develops hypertriglyceridemia. Increased LP-X content leads to cholestasis, blocks cholesterol excretion, and eventually leads to hyperlipidemia. C: Extensive immune expansion can result in hypoproteinemia and hyperlipidemia. D: GVHD alters the intestinal microenvironment and affects the synthesis of enzymes that regulate substances