FIGURE 4.

The mouse model of OAPS was obtained by injection of aPL, presenting as fetal loss and placenta abnormalities. (A) Schematic diagram of making OAPS mouse model. Administration by tail vein injection in mice to construction the OAPS mouse model. (B) Representative photographs of uterus morphology from normal mouse on P15. (C) Representative photographs of uterus morphology from OAPS mouse on P15. Injected with aPL during pregnancy to induce foetal loss. Abortion, stillbirth, growth restriction, and placental hematoma were observed in OAPS mouse models, as the arrow points out. Data are representative of observations in 5 mice per group