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Therapeutic effects of HCQ in animal models of APS
| FRF (%) | Foetus (mg) | Placenta (mg) | Weight difference (g) | No pregnant proportion | |
|---|---|---|---|---|---|
| CRTL | 4.5 ± 5.6 | 460.5 ± 49.4 | 105.6 ± 5.2 | 10.1 ± 1.5 | 11.80% |
| APS | 31 ± 6.4 | 345.8 ± 22.5 | 92.3 ± 1.7 | 10.4 ± 1.5 | 32.20% |
| APS + HCQ | 6.7 ± 7.1 | 445.3 ± 54.6 | 104.3 ± 4.9 | 9.8 ± 0.9 | 18.20% |
Notes: FRF was calculated as the number of resorptions divided by the total number of foetuses (resorptions plus viable).
Abbreviation: FRF, foetal resorption frequency.
