FIGURE 9.

LSD1 inhibitor ameliorated TLR4/NOX4 activation that was induced by renal IRI in mice. All mice were subjected to ischaemia 30 min and then reperfusion 24 h. (A–C) The regulation of LSD1 inhibitor on TLR4/NOX4 expression in mice after IRI, and quantification was also shown. (D–E) Representative pictures of immunohistochemistry for TLR4 and NOX4 (×400; scale bars = 40 μm). (n = 8). The results were expressed as mean ± SEM. *p < 0.05, when compared with the sham group. #p < 0.05, when compared with the IRI group