Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Graphical illustration of the model to estimate contamination rates via copying haplotypes from a haplotype reference panel. The target male X chromosome is modeled as a mosaic copy from a haplotype reference panel. In this specific case, the haplotype is copied from reference haplotype 4,2,1 (from left to right). The observed read counts at each biallelic marker are modeled as a mix of sequences from the endogenous and contaminant haplotypes and sequencing errors
