Table 1. Bisubstrate Inhibitors of SARS-CoV-2 Nsp14 MTase.

^aNA, not active, <15% inhibition at 50 μM.

^bNT, nontoxic, >95% cell viability at 50 μM. IC₅₀, EC₅₀ and CC₅₀ values were determined in at least duplicate and the averages were reported.