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. 2022 Jul 21;122(17):14066–14084. doi: 10.1021/acs.chemrev.1c01062

Figure 7.

Figure 7

Packing of the ribonucleoprotein (RNP) complex within spherical and ellipsoidal SARS-CoV-2 particles. (A) Representative tomogram slices (5 Å thick) of spherical and ellipsoid viral particles. RNPs are visible as granular densities within the viral lumen. (B) Hexon and pyramid in situ ultrastructure reconstructions of the RNP. There was an approximately 2-fold increase in pyramid RNP reconstructions in ellipsoid viruses compared to spherical viruses. (C) Representative RNP packing arrangements in spherical and ellipsoid SARS-CoV-2 virions. Adapted with permission from ref (47). Copyright 2020 Elsevier.