Table 2.

REACH (education+values) main online session content

	Content	Intended function
Part 1. Clarify and affirm values in domain of health and self-care	Participants identify values “that specifically motivate you to take care of yourself” using interactive content, and write freely about how the value is important to them, including examples of how it influenced what they did.	Clarify and affirm values prior to AET education, per studies showing more openness to health information after values affirmation [59, 60], but with a focus on health domain-specific (not general) values
Part 2. AET education	Described in Education Intervention (see Methods).	Educate participants about AET’s purpose, the importance of adherence, and how to manage common side effects; designed as an active control
Part 3. Values and perspective-taking	Participants complete interactive, ACT-based exercises that draw on values and perspective-taking linked to motivation for AET adherence.	Link core personal values to the value of adhering to AET, thereby bolstering personal motivation for AET adherence
Part 4. Creating a visual reminder	Participants select the top value that motivates them to take AET, upload a photo or phrase that captures this value, and design a sticker that features it to place on their Wisepill box.	Visually reinforce the link between participants’ values and adhering to AET by creating a positive, affective “cue to action” in the form of a values sticker