Comparison 5. Children: xylitol plus fluoride toothpaste versus fluoride toothpaste.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Caries increment at 2.5 to 3 years follow‐up (Prevented Fraction)	2		Prevented Fraction (Fixed, 95% CI)	0.13 [0.08, 0.18]
2 Caries increment at 2.5 to 3 years follow‐up (DFS)	2	4216	Mean Difference (IV, Fixed, 95% CI)	‐0.28 [‐0.42, ‐0.14]