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. 2022 Aug 2;12:13299. doi: 10.1038/s41598-022-17335-4

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Representative cross section of CT data sets of the chest region of a mouse reconstructed (A) without RG and (B) with RG and frame averaging. In green the segmented lung using the same threshold is partially overlaid. Clearly, in (B) both, less motion artifacts and a sharper delineation of the lung towards the rib cage are observed. This allows to study the anatomical shape of the lung in 3D as demonstrated in (C). Note, that the interface between lung and heart was not improved since no gating was performed for the movement of the heart. The figure was generated using imagej 1.53f www.imagej.nih.gov/ij/, gimp 2.10.28 www.gimp.organd scry (proprietary 3D render software).