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. 2022 Jul 15;36(8):877–896. doi: 10.1007/s40263-022-00936-y

Table 2.

Factors affecting the intrathecal spread of local anesthetics

Drug-specific factors Patient-specific factors Procedure-specific factors
Baricity Patient height Injection speed
Temperature Position Injection pressure
Viscosity Age Needle orientation
Dosage Anatomy Needle approach