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. 2021 Sep 13;29(4):1702–1709. doi: 10.1007/s12350-021-02781-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Systemic arterial micro-calcification was related to systemic arterial macro-calcification over five years. Correlation between systemic positron emission tomography-assessed arterial [¹⁸F]-sodium fluoride ([¹⁸F]NaF) uptake (expressed as _meantarget to background ratio (TBR), calculated by averaging ten TBRs (maximal standardized uptake value (SUVmax) divided by the mean standardized uptake value (SUVmean) of the blood pool)) and follow-up low dose computed tomography-assessed arterial macro-calcification (expressed as calcified plaque score, measured in whole aortic tree4)