Table 1.
Correlation between HIF-1α expression and clinicopathological characteristics in 69 oesophageal squamous cell carcinoma patients.
HIF-1α expression level | |||
---|---|---|---|
High (45) | Low (24) | P valuea | |
Gender | 0.275 | ||
Male | 37 | 17 | |
Female | 8 | 7 | |
Age (years) | |||
>68 | 23 | 11 | 0.676 |
≤68 | 22 | 13 | |
T stage | 0.015b | ||
1 | 8 | 13 | |
2 | 8 | 1 | |
3 | 26 | 9 | |
4 | 3 | 1 | |
N stage | |||
N0 | 20 | 8 | 0.023b |
N1 | 8 | 12 | |
N2 | 11 | 4 | |
N3 | 6 | 0 | |
Pathological stage | 0.321 | ||
I | 5 | 7 | |
II | 17 | 7 | |
III | 17 | 8 | |
IV | 6 | 2 | |
Infiltrative growth (INF) | 0.175 | ||
a | 2 | 4 | |
b | 41 | 18 | |
c | 2 | 2 | |
Lymphatic invasion | 0.280 | ||
Positive | 23 | 9 | |
Negative | 22 | 15 | |
Vascular invasion | 0.031b | ||
Positive | 37 | 14 | |
Negative | 8 | 10 | |
β-catenin expression | 0.003b | ||
High | 22 | 3 | |
Low | 23 | 21 | |
TCF4/TCF7L2 expression | 0.109 | ||
High | 26 | 9 | |
Low | 19 | 15 |
aStatistical significance is determined by the Chi-square test or Fisher’s exact test.
bThe bold figures in the table indicate that the P value is statistically significant.