Table 2.
Correlation between HIF-1α and TCF4/TCF7L2 expression and clinicopathological characteristics in 69 oesophageal squamous cell carcinoma patients.
| HIF-1α/TCF4 expression level | |||
|---|---|---|---|
| HIF-1αHigh/TCF4 High (26) | HIF-1αLow/TCF4 Low (15) | P valuea | |
| Gender | 0.064 | ||
| Male | 22 | 8 | |
| Female | 4 | 7 | |
| Age (years) | 0.393 | ||
| >68 | 12 | 9 | |
| ≤68 | 14 | 6 | |
| T stage | 0.019b | ||
| 1 | 4 | 9 | |
| 2 | 2 | 1 | |
| 3 | 18 | 5 | |
| 4 | 2 | 0 | |
| N stage | 0.002b | ||
| N0 | 12 | 4 | |
| N1 | 3 | 10 | |
| N2 | 8 | 1 | |
| N3 | 3 | 0 | |
| Pathological stage | 0.407 | ||
| I | 3 | 5 | |
| II | 9 | 5 | |
| III | 11 | 4 | |
| IV | 3 | 1 | |
| Infiltrative growth (INF) | 0.007b | ||
| a | 0 | 4 | |
| b | 25 | 10 | |
| c | 1 | 1 | |
| Lymphatic invasion | 0.837 | ||
| Positive | 13 | 7 | |
| Negative | 13 | 8 | |
| Vascular invasion | 0.012b | ||
| Positive | 23 | 8 | |
| Negative | 3 | 7 | |
aStatistical significance is determined by the Chi-square test or Fisher’s exact test.
bThe bold figures in the table indicate that the P value is statistically significant.