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. 2022 Jun 8;27(4):383–396. doi: 10.1007/s12192-022-01280-2

Fig. 4.

Fig. 4

ACY-1215 inhibits the BCR-ABL signaling pathway. (a) Co-IP was performed to detect the acetylation of Hsp90α. (b, c) Co-IP was used to detect the binding of BCR-ABL and Hsp90α with or without ACY-1215 treatment. (d) Western blot was used to detect the expression of p-BCR-ABL, p-STAT5, p-CRKL in CML cells