Table 2.
Univariate regression analysis to identify predictors of catheter-drainage failure
| Odds ratio | 95% CI | P value | |
|---|---|---|---|
| Baseline characteristics and CTSI | |||
| Age | 1.01 | [0.98; 1.04] | 0.5388 |
| Male | 1.08 | [0.33; 3.52] | 0.8944 |
| BMI | 1.11 | [1.01; 1.22] | 0.0246 |
| SOFA | 1.02 | [0.94; 1.14] | 0.39 |
| Persistent organ failurea, after the first 48 h | |||
| Respiratory failure | 2.40 | [0.74; 7.75] | 0.1431 |
| Hemodynamic failure | 2.49 | [0.60; 10.32] | 0.2071 |
| Renal failure | 1.38 | [0.30; 6.27] | 0.6760 |
| Complications during the 24 h before first drainage | |||
| Respiratory failure | 4.62 | [1.62; 13.21] | 0.0043 |
| Hemodynamic failure | 1.86 | [0.56; 6.15] | 0.3078 |
| Renal failure | 1.76 | [0.40; 7.67] | 0.4531 |
| Data on last CT before drainage | |||
| CTSI before drainage | 1.20 | [0.98; 1.48] | 0.07 |
| % of pancreatic necrosis | |||
| Pancreatic necrosis < 30% | 0.46 | [0.17; 1.25] | 0.12 |
| Pancreatic necrosis ≥ 30 < 50% | 0.69 | [0.19; 2.55] | 0.58 |
| Pancreatic necrosis ≥ 50% | 3.47 | [1.07; 11.19] | 0.03 |
| Heterogeneous collection | 2.44 | [0.84; 7.06] | 0.10 |
| Gas bubbles in collection on CT | 1.23 | [0.38; 4.06] | 0.72 |
| Acute necrotic collection | 0.00 | [0.00; I]* | 0.9799 |
| Walled-off necrosis | 1.87 | [0.32; 11.00] | 0.4883 |
| PSM vein thrombosis | 0.98 | [0.34; 2.84] | 0.96 |
| PSM vein narrowing | 2.33 | [0.86; 6.29] | 0.09 |
| Drainage modalities | |||
| Time from diagnosis to drainage (per additional day) | 1.04 | [1.00; 1.07] | 0.0663 |
| Antibiotic therapy ≥ 48 h before drainage | 0.72 | [0.27; 1.93] | 0.5154 |
| Second drainage (percutaneous or endoscopic) | 15.05 | [1.80; 125.95] | 0.0124 |
95% CI 95% confidence interval, CTSI computed tomography severity index, BMI: body mass index, SOFA Sequential Organ Failure Assessment, PSM: portosplenomesenteric. Bold numbers indicate p<=0.05
aOrgan failure was defined as a SOFA subscore ≥ 2 for the respiratory, renal, and/or hemodynamic components