Table 1:

Demographic characteristics of the analysis cohort of patients with cirrhosis.

	Full Analysis Cohort	Incident HCC cases during follow-up	Cirrhosis patients with no HCC during follow-up	P-value (HCC vs Control)*
Number of subjects	534	50	484
Age at study consent (years)	63.2 (6.6)	64.7 (5.7)	63.0 (6.7)	0.13
Race				0.13
White	263 (49%)	21 (42%)	242 (50%)
Black	206 (39%)	18 (36%)	188 (39%)
Latino	52 (10%)	9 (18%)	43 (9%)
Other	13 (2%)	2 (4%)	11 (2%)
Gender				0.62
Male	522 (98%)	50 (100%)	472 (98%)
Female	12 (2%)	0	12 (2%)
Number of study visits
1	161 (30%)	17 (34%)	144 (30%)
2	132 (25%)	12 (24%)	120 (25%)
3	108 (20%)	12 (24%)	96 (20%)
4	70 (13%)	3 (6%)	67 (14%)
5 or more	63 (13%)	6 (12%)	57 (12%)
Baseline Lab Tests, mean (SD)
ALT (U/L)	49.2 (48.8)	46.1 (32.1)	49.5 (50.3)	0.70
AST (U/L)	56.4 (48.4)	60.6 (43.7)	56.0 (48.9)	0.09
ALP (U/L)	95.4 (62.1)	110.6 (48.6)	93.8 (63.2)	<0.001
GGT (U/L)	118.0 (152.6)	129.0 (130.3)	116.8 (154.9)	0.11
Platelets (K/cmm)	149.0 (67.4)	115.5 (45.2)	152.5 (68.4)	<0.001
Albumin (g/L)	3.7 (0.6)	3.5 (0.9)	3.7 (0.6)	<0.001
T-Bilirubin (umol/L)	1.4 (5.4)	1.3 (0.8)	1.4 (5.7)	0.04
Creatinine (umol/L)	1.0 (0.7)	0.9 (0.2)	1.0 (0.7)	0.07
Etiology				N/A (non-mutually exclusive etiology categories)
HCV	381 (71%)	42 (84%)	339 (70%)
Active HCV	92 (24%)	19 (45%)	73 (22%)
Receiving treatment	147 (39%)	18 (43%)	129 (38%)
Treated with SVR	239 (63%)	13 (31%)	226 (67%)
HBV	12 (2%)	0	12 (2%)
Alcoholic liver disease	326 (61%)	36 (72%)	290 (60%)
NAFLD/NASH	114 (21%)	10 (20%)	104 (21%)
Others	24 (4%)	4 (8%)	20 (4%)

^†Data reported are means and standard deviations for continuous variables and counts and percentages for categorical variables.

^*P-values from Mann-Whitney U-test for continuous variables and Fisher’s exact test for categorical variables