Figure 2.

MRI in patient 2 at the time of diagnosis (upper arrow) and 5 months later (lower arrow). (A) Pre-contrast mid-sagittal T1-weighted view revealing a pituitary mass of intermediate and homogeneous signal intensity. (B) Pre-contrast T1-weighted view showing similar findings. (C) Post-contrast T1-weighted view in similar slice location as (B) revealing only a very thin marginal enhancement of the mass with complete devascularisation of its core. (D) Coronal T2-weighted view in similar slice location as (B, C) revealing strong hypointensity of the mass. (E) Pre-contrast mid-sagittal T1-weighted view in similar slice location as (A) revealing only a qualitative change with appearance of hypersignal intensity at anterior border of the mass (arrow) due to increase in protein concentration. (F) Pre-contrast T1-weighted view in similar slice location as (B) confirming subtle intensity changes (arrows). (G) Post-contrast T1-weighted view in similar slice location as (C) failing to reveal any change when compared to (C). (H) Coronal T2-weighted view in similar slice location as (D) revealing appearance of subtle areas of slightly increased signal intensity (arrows) mainly due to technical differences between (D) and (H).