. 2022 Jun 13;11(7):e220062. doi: 10.1530/EC-22-0062
This work is licensed under a Table 1.
Comparison of patient and tumor characteristics, including preoperative biochemical laboratory values, in patients with parathyroid carcinoma and parathyroid adenoma.
| Variables | Carcinoma (n = 36) | Adenoma (n = 50) | P - value |
|---|---|---|---|
| Age (years) | 55.0 (46–68.5) | 59.5 (46–68) | 0.8679 |
| Gender (male/female) | 10/26 (27.8/72.2) | 15/35 (30.0/70.0) | 0.8228 |
| Tumor size (mm) | 29 (18–36) | 17 (14–24) | 0.0002 |
| Intact PTH level (pg/mL) | 246.5 (160.0–444.5) | 161.0 (118.0–205.5) | 0.0003 |
| Calcium level (mg/dL) | 11.5 (10.9–12.8) | 10.9 (10.6–11.3) | 0.0048 |
| Creatinine (mg/dL) | 0.74 (0.60–0.90) | 0.76 (0.57–0.86) | 0.6455 |
| ALP (U/L) | 350 (218–512) | 294 (234–386) | 0.3416 |
| WBC (/μL) | 5960 (4880–6900) | 5490 (4743–6605) | 0.3416 |
| Neutrophils (/μL) | 3648 (2936–4384) | 3231 (2698–4207) | 0.1415 |
| Lymphocytes (/μL) | 1784 (1430–2346) | 1789 (1475–2076) | 0.8233 |
| Monocytes (/μL) | 372 (325–479) | 292 (259–352) | 0.0003 |
| Plt (×104/μL) | 23.1 (20.1–28.5) | 24.8 (20.6–27.9) | 0.7109 |
| NLR | 1.90 (1.64–2.46) | 1.89 (1.48–2.22) | 0.4023 |
| PLR | 141.1 (103.6–160.4) | 143.4 (110.4–164.8) | 0.6418 |
| LMR | 4.54 (3.38–6.28) | 6.00 (4.40–7.50) | 0.0062 |
Data were expressed as number (%) or median (interquartile range/IQR). Bold indicates statistical significance, P < 0.05. Normal range; intact PTH: 15–65 pg/mL, calcium: 8.5–10.0 mg/dL, creatinine: 0.46–1.09 mg/dL, ALP: 38–113 U/L.
ALP, alkaline phosphatase; cLND, central lymph node dissection; hTx, hemithyroidectomy; NLR, neutrophil-to-lymphocyte ratio; PTH, parathyroid hormone; Plt, platelet count; PLR, platelet-to-lymphocyte ratio; PTx, parathyroidectomy; LMR, lymphocyte-to-monocyte ratio; WBC, white blood cell.