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. 2022 Jun 23;11(8):e220064. doi: 10.1530/EC-22-0064

Table 1.

Top differentially expressed genes in adrenal glands in Dex-treated male mice.

Top upregulated genes Top downregulated genes
Gene namea Average FPKM Average FPKM Fold change
Saline Dex Fold change Gene nameb Saline Dex
Abca1 10.2 42.8 4.20 Nr4a1 138.0 14.0 0.10
Pdk4 3.0 11.7 3.83 2010003K11Rik 16.3 3.2 0.20
Zbtb16 6.6 25.4 3.83 Gm13889 18.9 4.2 0.22
Chrna7 3.8 14.2 3.79 2010109I03Rik 14.7 4.1 0.28
Ddit4 28.6 107.9 3.77 Tnfrsf12a 225.4 70.5 0.31
Fam107a 5.3 19.0 3.60 Mob4 78.9 25.9 0.33
Nt5e 4.1 13.8 3.40 Apoc4 11.6 3.9 0.34
Fzd4 3.6 11.6 3.25 Coq10b 63.5 21.6 0.34
Greb1 20.3 63.4 3.12 Cryba4 24.9 9.0 0.36
Lrg1 9.2 28.3 3.07 Yam1 6933.1 2565.2 0.37
Lnpep 8.2 24.2 2.94 Mapkapk3 13.9 5.3 0.38
Maf 4.6 13.3 2.87 Fdx1 2978.8 1129.6 0.38
Tsc22d3 28.3 80.4 2.84 Avpi1 60.7 23.1 0.38
Tbx20 4.8 13.6 2.83 Junb 44.5 17.0 0.38
Rin2 6.6 18.2 2.74 Ldlr 31.9 12.3 0.38
Vcam1 9.3 25.4 2.72 Hba-a2 17.0 6.7 0.40
AW551984 3.9 10.4 2.70 Tubb6 121.8 49.0 0.40
Dock10 4.1 11.0 2.68 Ptp4a1 42.6 17.6 0.41
Klf15 9.5 25.5 2.67 Smim3 31.0 12.8 0.41
Rab3c 8.7 23.1 2.65 Atf4 146.0 60.9 0.42
Pde10a 6.0 15.8 2.65 Nr5a1 330.6 138.7 0.42
Arl4d 5.6 14.5 2.60 Scx 32.3 13.6 0.42
Errfi1 14.2 36.6 2.58 Dusp10 10.0 4.2 0.42
Hmgcs2 4.8 12.3 2.54 Hes6 174.1 75.7 0.43
Atp7a 5.4 13.7 2.54 Srrd 11.4 5.0 0.44
Fkbp5 47.6 121.0 2.54 Etnk2 22.9 10.1 0.44
Bmp4 5.4 13.7 2.53 Gm10275 16.6 7.5 0.45
Ston1 8.1 20.5 2.52 Alas1 423.9 191.0 0.45
Ptprn2 5.4 13.6 2.52 Tmem120a 29.4 13.6 0.46
Irs2 4.3 10.8 2.49 Adamts1 12.6 5.9 0.46
Bdkrb2 4.5 11.2 2.47 Creb3l1 19.1 9.1 0.47
Klhl24 6.0 14.9 2.47 Zswim4 16.5 7.9 0.48
Pdp1 11.9 29.3 2.47 Dusp14 12.4 5.9 0.48
Tgfbr3 38.4 93.2 2.43 Fam222a 34.9 16.7 0.48
Slc9a7 5.0 12.0 2.41 Akr1b7 1279.3 611.1 0.48
Rims3 5.1 12.3 2.40 Cldn5 11.8 5.7 0.48
Osbpl3 19.7 47.1 2.39 Naa38 20.3 9.8 0.48
Cebpd 16.7 39.6 2.36 2310009B15Rik 16.1 7.8 0.48
Arrdc2 4.4 10.1 2.32 Agtr1b 13.5 6.6 0.49
Adcyap1r1 12.2 28.3 2.31 RP24-139E15.1 16.4 8.1 0.49
Klhl11 5.5 12.7 2.31 Lsm5 14.5 7.2 0.49
Ncoa7 5.8 13.4 2.30 Esm1 18.9 9.3 0.50
Mcf2l 4.8 10.9 2.30 Mir22hg 15.2 7.5 0.50
Map3k6 8.7 19.9 2.29 Hbb-bt 19.5 9.7 0.50
Lars2 270.7 134.8 0.50

aOnly list the genes that have FPKM > 10 in the Dex-treated group; bOnly list the genes that have FPKM > 10 in the saline-treated group.