Table 3.
In vitro studies investigating the effects of polyphenols against SARS-CoV-2 infection
| Polyphenols | Cell Model | SARS-CoV-2 strain | Concentration for used | References |
|---|---|---|---|---|
| Quercetin | Huh-7 | Human coronavirus 229E | 2.5uM~50uM | 111 |
| Vero E6 cells | SARS-CoV-2 strain 026V-03883 | Compound 1: 200uM~500uM; Compound 2d: 10uM~100uM | 112 | |
| EGCG | Huh-7 | Human coronavirus 229E | 2.5uM~50M | 111 |
| HEK293T-hACE2 and Vero E6 cells | SARS-CoV strain Frankfurt-1 | 1.25ug/ml ~25ug/ml | 118 | |
| Resveratrol | Vero E6 cells, Calu-3 cells and primary human bronchial epithel (PBECs) | SARS-CoV-2 strain NL/2020 | 15uM~150uM | 126 |
| Vero E6 cells | SARS-CoV-2 (BetaCoV/Shenzhen/SZTH-003/2020 strain) | 1.56uM~200uM | 127 | |
| Curcumin | hACE2/A549 | eGFP-luciferase-SARS-CoV-2 pseudo-typed particles | 2.5~100 ug/ml | 138 |
| Vero E6 cells, | SARS-CoV-2 D614G strain and Delta variant | 1.25~10 ug/ml | 136 | |
| Vero E6 cells and Calu-3 cells | SARS-CoV-2 isolated form hospital | 1ug/ml~125ug/ml | 137 |